Qualitative and Quantitative Perfusion Parameters Determined by 3D Single-Shot GRASE ASL MR Imaging
نویسندگان
چکیده
منابع مشابه
Improved ASL Imaging with 3D GRASE PROPELLER
Introduction: Arterial Spin Labeling (ASL) uses blood water as an endogenous tracer to non-invasively measure cerebral blood flow. In a previous study, Günther et al. (1) has shown a near 3-fold improvement in perfusion signal-to-noise ratio (SNR) with single-shot 3D GRASE compared to conventional 2D EPI. However, a limitation of 3D GRASE is through-plane blurring caused by T2 decay. Reducing t...
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For perfusion-based functional magnetic resonance imaging, the previously introduced flow-sensitive alternating inversion recovery (FAIR) technique is combined with single-shot RARE (rapid acquisition with relaxation enhancement) and GRASE (gradient and spin echo) imaging sequences. The advantages of these sequences compared to commonly used echo-planar imaging (EPI) are an increased signal-to-...
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The major drawback to quantitative perfusion imaging using arterial spin labeling (ASL) techniques is the need to acquire two images (tag and control), which must be subtracted in order to obtain a perfusion-weighted image. This can potentially result in misregistration artifacts, especially in lung imaging, due to varying lung inflation levels in different breath-holds. In this work a double i...
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The Gradient and Spin Echo (GRASE) pulse sequences has been used primarily for T2 weighted imaging, with the spin echoes of the CPMG sequence utilized for the center of k-space. While to date, T2 contrast has been a fundamental feature of GRASE, it is possible to obtain T2* and BOLD signal contrast mechanisms in GRASE by shifting the central region of k-space from spin echoes to gradient echoes...
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Arterial Spin Labeling (ASL) is a technique capable of measuring cerebral blood flow (CBF) in humans. However, ASL is limited by low sensitivity given blood is ~3% by volume in brain parenchyma. Single-shot 3D GRASE ASL technique has made possible whole brain coverage with over twice the signal-tonoise ratio (SNR) of 2D EPI ASL. To achieve even higher spatial resolution in fast acquisitions, a ...
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ژورنال
عنوان ژورنال: Open Journal of Medical Imaging
سال: 2012
ISSN: 2164-2788,2164-2796
DOI: 10.4236/ojmi.2012.21001